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The discovery of Chlamydia

Introduction

Chlamydia is a microorganism that is different from bacteria and viruses. The original body is a gram-negative pathogen, spread in nature is widespread. It is not the synthesis of high-energy compounds ATP, GTP ability, must be provided by the host cells, and thus become energy parasites, mostly spherical, piled, with cell walls, generally parasitic in animal cells. Once upon a time they were classified as viruses and later found to be self-contained. It is a larger than the virus, smaller than the bacteria of the prokaryotic microorganisms, spherical, diameter only O.3-0.5 microns, it has no athletic ability, widely parasitic in humans, mammals and birds, only a few have pathogenicity. CHEMTRON chlamydia testing for the most widely used domestic chlamydia testing tools.

The main difference between Chlamydia and virus is that it has DNA, RNA two kinds of nucleic acids, ribosomes and a similar cell wall of the membrane and proliferation in the way of two split, can be antibiotic inhibition.

There are three known chlamydia associated with human disease, namely Chlamydia psittaci, Chlamydia trachomatis and Chlamydia pneumoniae. These three kinds of chlamydia can cause lung infection. Chlamydia psittaci can infect humans by contact and inhalation through tissues, blood and feces of birds infected with Chlamydia species such as parrots, peacocks, chickens, ducks, pigeons. Chlamydia trachomatis and Chlamydia pneumoniae spread in the human with respiratory droplets, maternal, child contact and sexual contact, etc.

 

Basic characteristic

Chlamydia (Chlamydia) is a class of bacteria through the filter, strict intracellular parasites, a unique developmental cycle of prokaryotic micro-organisms. In the past that is a virus, now belong to the scope of bacteria. Chlamydia is widely parasitic in humans, birds and mammals. Can cause human diseases have Chlamydia trachomatis, Chlamydia pneumoniae, Chlamydia psittaci.

1.the volume is greater than the virus, about 250 ~ 500nm, can be found under the optical microscope.

2.containing DNA and RNA.

3. with a cell wall, but no peptidoglycan, only a small amount of the cell wall, the disulfide bond of the polypeptide as a stent.

4. a variety of antibiotics sensitive.

5. with some enzymes but not perfect, these enzymes lack the role of metabolic energy generated by the main cells to provide. In the chicken embryo yolk sac and a variety of cell growth and reproduction.

6.a unique development cycle, only within the living cells in order to reproduce in two divisions.

7. Antibacterial and drug-sensitive bacteria.

 

Discovery and research

Chlamydia was first reported by Miyagawa (1935) as a Miyagawa body from the chromosome of a patient with inguinal lymphogranuloma and was named Miyagawanella (E. Brumpt, 1938). For example, Rickettsiaformis, Neor-ickettsia and the like, which are known as rickettsia, are also called "psittacosis and mphogranvloma virus" as a virus, and many other names have been mentioned, Virus, PLV), Psittacosis virus group (Psittacosis virus group), quite chaotic. Chlamydiales (L.A.Pagei et al., 1971) are now classified according to Berger's classification.

Chlamydia has been shown to have glucose metabolic activity and protein synthesis; cell proliferation in the cell, do not enter the cell quality. Infested particles enter the cell by phagocytosis and are converted into particles generally called reticular structures. The reticular structure was proliferated by cleavage and matured into infected particles at the later stage. Therefore, although the incubation period as the continuity of the particles is not maintained during the growth cycle, it is apparent from the appearance that there is a period corresponding to the incubation period because the infectivity of the network structure is not confirmed.


TAG:  Chlamydia
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Read:  2016-11-15 13:01:08  Glory Science Life science source - ELISA Kits - Antibodies - Research Products
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