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Anti-HMGB 1

Anti-HMGB 1
Anti-HMGB 1

Background Information:
Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and
lipid hydroperoxides. Members of the murine GSTP (glutathione S-transferase pi) family, termed Gstp1 and Gstp2,
are linked to drug resistance and are markers for many cancers. Gstp proteins modulate cell signaling by interacting
with c-Jun N-terminal kinase (JNK), and may play a protective role in the development of spontaneous tumors. Gstp
has been found in substantia nigra and may be associated with reactive oxygen species-induced neurological
disorders such as Parkinson’s disease and may additionally protect against endothelial dysfunction induced by
tobacco smoke exposure.
KeyApplications:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

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